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Interaction of Oxazaphosphorines with Multidrug Resistance-Associated Protein 4 (MRP4)

Multidrug resistance-associated protein 4 (MRP4) is an organic anion efflux pump capable of transporting nucleoside, nucleotide analogs, and cyclic nucleotide. MRP4 could have an influence on the resistance and transport of the two oxazaphosphorines, cyclophosphamide (CP) and ifosfamide (IF). V/HepG...

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Detalhes bibliográficos
Main Authors: Zhang, Jing, Ng, Ka-Yun, Ho, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895452/
https://ncbi.nlm.nih.gov/pubmed/20405259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9189-x
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