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Interaction of Oxazaphosphorines with Multidrug Resistance-Associated Protein 4 (MRP4)

Multidrug resistance-associated protein 4 (MRP4) is an organic anion efflux pump capable of transporting nucleoside, nucleotide analogs, and cyclic nucleotide. MRP4 could have an influence on the resistance and transport of the two oxazaphosphorines, cyclophosphamide (CP) and ifosfamide (IF). V/HepG...

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Hlavní autoři: Zhang, Jing, Ng, Ka-Yun, Ho, Paul C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895452/
https://ncbi.nlm.nih.gov/pubmed/20405259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9189-x
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