CSL controls telomere maintenance and genome stability in human dermal fibroblasts

Genomic instability is a hallmark of cancer. Whether it also occurs in Cancer Associated Fibroblasts (CAFs) remains to be carefully investigated. Loss of CSL/RBP-Jκ, the effector of canonical NOTCH signaling with intrinsic transcription repressive function, causes conversion of dermal fibroblasts in...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bottoni, Giulia, Katarkar, Atul, Tassone, Beatrice, Ghosh, Soumitra, Clocchiatti, Andrea, Goruppi, Sandro, Bordignon, Pino, Jafari, Paris, Tordini, Fabio, Lunardi, Thomas, Hoetzenecker, Wolfram, Neel, Victor, Lingner, Joachim, Paolo Dotto, G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715699/
https://ncbi.nlm.nih.gov/pubmed/31467287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11785-7
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