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Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation
Cancer-associated fibroblasts (CAFs) are important for tumor initiation and promotion. CSL, a transcriptional repressor and Notch mediator, suppresses CAF activation. Like CSL, ATF3, a stress-responsive transcriptional repressor, is down-modulated in skin cancer stromal cells, and Atf3 knockout mice...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551580/ https://ncbi.nlm.nih.gov/pubmed/28684431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170724 |
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