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Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism
Cancer-associated fibroblasts (CAFs) are important at all tumor stages. CSL/RBPJκ suppresses the gene expression program leading to CAF activation and associated metabolic reprogramming, as well as autophagy. Little is known about CSL protein turnover, especially in the tumor microenvironment. We re...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200139/ https://ncbi.nlm.nih.gov/pubmed/30231994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.043 |
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