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PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

The Notch/CSL pathway plays an important role in skin homeostasis and carcinogenesis. CSL, the key effector of canonical Notch signaling endowed with an intrinsic transcription repressive function, suppresses stromal fibroblast senescence and Cancer Associated Fibroblast (CAF) activation through dir...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jo, Seung-Hee, Kim, Dong Eun, Clocchiatti, Andrea, Dotto, G. Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312270/
https://ncbi.nlm.nih.gov/pubmed/27542230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11227
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