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The Ulk3 kinase is critical for convergent control of cancer associated fibroblast activation by CSL and Gli

The connection between signaling pathways activating cancer associated fibroblasts (CAFs) remains to be determined. Metabolic alterations linked to autophagy have also been implicated in CAF activation. CSL/RBPJ, a transcriptional repressor that mediates Notch signaling, suppresses gene expression p...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Goruppi, Sandro, Procopio, Maria-Giuseppina, Jo, Seunghee, Clocchiatti, Andrea, Neel, Victor, Dotto, G. Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616185/
https://ncbi.nlm.nih.gov/pubmed/28877478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.048
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