Tumor cell–intrinsic EPHA2 suppresses antitumor immunity by regulating PTGS2 (COX-2)

Resistance to immunotherapy is one of the biggest problems of current oncotherapeutics. While T cell abundance is essential for tumor responsiveness to immunotherapy, factors that define the T cell–inflamed tumor microenvironment are not fully understood. We used an unbiased approach to identify tum...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Markosyan, Nune, Li, Jinyang, Sun, Yu H., Richman, Lee P., Lin, Jeffrey H., Yan, Fangxue, Quinones, Liz, Sela, Yogev, Yamazoe, Taiji, Gordon, Naomi, Tobias, John W., Byrne, Katelyn T., Rech, Andrew J., FitzGerald, Garret A., Stanger, Ben Z., Vonderheide, Robert H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715369/
https://ncbi.nlm.nih.gov/pubmed/31162144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127755
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