Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function

Cyclooxygenase-2 (COX-2) expression is associated with poor prognosis across a range of human cancers, including breast cancer. The contribution of tumor cell-derived COX-2 to tumorigenesis has been examined in numerous studies; however, the role of stromal-derived COX-2 is ill-defined. Here, we exa...

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Detalhes bibliográficos
Main Authors: Chen, Edward P., Markosyan, Nune, Connolly, Emma, Lawson, John A., Li, Xuanwen, Grant, Gregory R., Grosser, Tilo, FitzGerald, Garret A., Smyth, Emer M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123643/
https://ncbi.nlm.nih.gov/pubmed/24590894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu053
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