Φορτώνει......
Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation
We describe the design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing a squaramide-derived scaffold as the P2 ligand in combination with a (R)-hydroxyethylamine ine sulfonamide isostere. Inhibitor 3h with an N-methyl-3-(R)-aminotetrahydrofuranyl squaramide P2-lig...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Bioorg Med Chem Lett |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6711809/ https://ncbi.nlm.nih.gov/pubmed/31416666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.08.006 |
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