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The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice

The brush of a feather or a pinprick are perceived as distinct sensations because they are detected by discrete cutaneous sensory neurons. Inflammation or nerve injury can disrupt this sensory coding and result in maladaptive pain states, including mechanical allodynia, the development of pain in re...

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Bibliografski detalji
Izdano u:Sci Transl Med
Glavni autori: Murthy, Swetha E., Loud, Meaghan C., Daou, Ihab, Marshall, Kara L., Schwaller, Frederick, Kühnemund, Johannes, Francisco, Allain G., Keenan, William T., Dubin, Adrienne E., Lewin, Gary R., Patapoutian, Ardem
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709986/
https://ncbi.nlm.nih.gov/pubmed/30305457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat9897
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