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The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice

The brush of a feather or a pinprick are perceived as distinct sensations because they are detected by discrete cutaneous sensory neurons. Inflammation or nerve injury can disrupt this sensory coding and result in maladaptive pain states, including mechanical allodynia, the development of pain in re...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Murthy, Swetha E., Loud, Meaghan C., Daou, Ihab, Marshall, Kara L., Schwaller, Frederick, Kühnemund, Johannes, Francisco, Allain G., Keenan, William T., Dubin, Adrienne E., Lewin, Gary R., Patapoutian, Ardem
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709986/
https://ncbi.nlm.nih.gov/pubmed/30305457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat9897
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