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Closing the DNA replication cycle: from simple circular molecules to supercoiled and knotted DNA catenanes

Due to helical structure of DNA, massive amounts of positive supercoils are constantly introduced ahead of each replication fork. Positive supercoiling inhibits progression of replication forks but various mechanisms evolved that permit very efficient relaxation of that positive supercoiling. Some o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Schvartzman, Jorge B, Hernández, Pablo, Krimer, Dora B, Dorier, Julien, Stasiak, Andrzej
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698734/
https://ncbi.nlm.nih.gov/pubmed/31276584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz586
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