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DNA supercoiling inhibits DNA knotting

Despite the fact that in living cells DNA molecules are long and highly crowded, they are rarely knotted. DNA knotting interferes with the normal functioning of the DNA and, therefore, molecular mechanisms evolved that maintain the knotting and catenation level below that which would be achieved if...

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Detalhes bibliográficos
Main Authors: Burnier, Yannis, Dorier, Julien, Stasiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528182/
https://ncbi.nlm.nih.gov/pubmed/18658246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn467
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