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DNA supercoiling inhibits DNA knotting
Despite the fact that in living cells DNA molecules are long and highly crowded, they are rarely knotted. DNA knotting interferes with the normal functioning of the DNA and, therefore, molecular mechanisms evolved that maintain the knotting and catenation level below that which would be achieved if...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2528182/ https://ncbi.nlm.nih.gov/pubmed/18658246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn467 |
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