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DNA supercoiling inhibits DNA knotting

Despite the fact that in living cells DNA molecules are long and highly crowded, they are rarely knotted. DNA knotting interferes with the normal functioning of the DNA and, therefore, molecular mechanisms evolved that maintain the knotting and catenation level below that which would be achieved if...

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書目詳細資料
Main Authors: Burnier, Yannis, Dorier, Julien, Stasiak, Andrzej
格式: Artigo
語言:Inglês
出版: Oxford University Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528182/
https://ncbi.nlm.nih.gov/pubmed/18658246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn467
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