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Closing the DNA replication cycle: from simple circular molecules to supercoiled and knotted DNA catenanes

Due to helical structure of DNA, massive amounts of positive supercoils are constantly introduced ahead of each replication fork. Positive supercoiling inhibits progression of replication forks but various mechanisms evolved that permit very efficient relaxation of that positive supercoiling. Some o...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Schvartzman, Jorge B, Hernández, Pablo, Krimer, Dora B, Dorier, Julien, Stasiak, Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698734/
https://ncbi.nlm.nih.gov/pubmed/31276584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz586
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