Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes

Chikungunya virus (CHIKV) is an emerging mosquito-borne virus that has caused explosive outbreaks worldwide. Although neutralizing monoclonal antibodies (mAbs) against CHIKV inhibit infection in animals, the contribution of Fc effector functions to protection remains unknown. Here, we evaluated the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Immunol
Egile Nagusiak: Fox, Julie M., Roy, Vicky, Gunn, Bronwyn M., Huang, Ling, Fong, Rachel H., Edeling, Melissa A., Mack, Matthias, Fremont, Daved H., Doranz, Benjamin J., Johnson, Syd, Alter, Galit, Diamond, Michael S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698136/
https://ncbi.nlm.nih.gov/pubmed/30796092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aav5062
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