Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes

Chikungunya virus (CHIKV) is an emerging mosquito-borne virus that has caused explosive outbreaks worldwide. Although neutralizing monoclonal antibodies (mAbs) against CHIKV inhibit infection in animals, the contribution of Fc effector functions to protection remains unknown. Here, we evaluated the...

詳細記述

保存先:
書誌詳細
出版年:Sci Immunol
主要な著者: Fox, Julie M., Roy, Vicky, Gunn, Bronwyn M., Huang, Ling, Fong, Rachel H., Edeling, Melissa A., Mack, Matthias, Fremont, Daved H., Doranz, Benjamin J., Johnson, Syd, Alter, Galit, Diamond, Michael S.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698136/
https://ncbi.nlm.nih.gov/pubmed/30796092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aav5062
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