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Structural basis of Flavivirus NS1 assembly and antibody recognition

The Flavivirus nonstructural protein 1 (NS1) is a conserved, membrane-associated and secreted glycoprotein with replication and immune evasion functions. Secreted NS1 is a hexameric, barrel-shaped lipoprotein that can bind back to the plasma membrane of cells. Antibodies targeting cell surface-assoc...

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Detalhes bibliográficos
Main Authors: Edeling, Melissa A., Diamond, Michael S., Fremont, Daved H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964132/
https://ncbi.nlm.nih.gov/pubmed/24594604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322036111
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