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Structural basis of Flavivirus NS1 assembly and antibody recognition
The Flavivirus nonstructural protein 1 (NS1) is a conserved, membrane-associated and secreted glycoprotein with replication and immune evasion functions. Secreted NS1 is a hexameric, barrel-shaped lipoprotein that can bind back to the plasma membrane of cells. Antibodies targeting cell surface-assoc...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3964132/ https://ncbi.nlm.nih.gov/pubmed/24594604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322036111 |
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