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A Short N-Terminal Peptide Motif on Flavivirus Nonstructural Protein NS1 Modulates Cellular Targeting and Immune Recognition

Flavivirus NS1 is a versatile nonstructural glycoprotein, with intracellular NS1 functioning as an essential cofactor for viral replication and cell surface and secreted NS1 antagonizing complement activation. Even though NS1 has multiple functions that contribute to virulence, the genetic determina...

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Détails bibliographiques
Auteurs principaux: Youn, Soonjeon, Cho, Hyelim, Fremont, Daved H., Diamond, Michael S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937659/
https://ncbi.nlm.nih.gov/pubmed/20592095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00775-10
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