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Antagonism of the complement component C4 by flavivirus nonstructural protein NS1

The complement system plays an essential protective role in the initial defense against many microorganisms. Flavivirus NS1 is a secreted nonstructural glycoprotein that accumulates in blood, is displayed on the surface of infected cells, and has been hypothesized to have immune evasion functions. H...

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Detalhes bibliográficos
Main Authors: Avirutnan, Panisadee, Fuchs, Anja, Hauhart, Richard E., Somnuke, Pawit, Youn, Soonjeon, Diamond, Michael S., Atkinson, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856034/
https://ncbi.nlm.nih.gov/pubmed/20308361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20092545
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