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Complement-Mediated Neutralization of Dengue Virus Requires Mannose-Binding Lectin

Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate immune system that binds specific mannose-containing glycans on the surfaces of microbial agents and initiates complement activation via the lectin pathway. Prior studies showed that MBL-dependent activation of...

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Detalhes bibliográficos
Main Authors: Avirutnan, Panisadee, Hauhart, Richard E., Marovich, Mary A., Garred, Peter, Atkinson, John P., Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236064/
https://ncbi.nlm.nih.gov/pubmed/22167226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00276-11
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