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Binding of Flavivirus Non-structural Protein NS1 to C4b Binding Protein Modulates Complement Activation

The complement system plays a pivotal protective role in the innate immune response to many pathogens including Flaviviruses. Flavivirus NS1 is a secreted non-structural glycoprotein that accumulates in plasma to high levels and is displayed on the surface of infected cells but is absent from viral...

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Autori principali: Avirutnan, Panisadee, Hauhart, Richard E., Somnuke, Pawit, Blom, Anna M., Diamond, Michael S., Atkinson, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119735/
https://ncbi.nlm.nih.gov/pubmed/21642539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100750
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