Experimental colitis in IL‐10‐deficient mice ameliorates in the absence of PTPN22

Interleukin (IL)‐10 plays a key role in controlling intestinal inflammation. IL‐10‐deficient mice and patients with mutations in IL‐10 or its receptor, IL‐10R, show increased susceptibility to inflammatory bowel diseases (IBD). Protein tyrosine phosphatase, non‐receptor type 22 (PTPN22) controls imm...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Exp Immunol
Prif Awduron: Jofra, T., Galvani, G., Cosorich, I., De Giorgi, L., Annoni, A., Vecchione, A., Sorini, C., Falcone, M., Fousteri, G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Editors’ Choice
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693971/
https://ncbi.nlm.nih.gov/pubmed/31194881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13339
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