Experimental colitis in IL‐10‐deficient mice ameliorates in the absence of PTPN22

Interleukin (IL)‐10 plays a key role in controlling intestinal inflammation. IL‐10‐deficient mice and patients with mutations in IL‐10 or its receptor, IL‐10R, show increased susceptibility to inflammatory bowel diseases (IBD). Protein tyrosine phosphatase, non‐receptor type 22 (PTPN22) controls imm...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Exp Immunol
Egile Nagusiak: Jofra, T., Galvani, G., Cosorich, I., De Giorgi, L., Annoni, A., Vecchione, A., Sorini, C., Falcone, M., Fousteri, G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Editors’ Choice
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693971/
https://ncbi.nlm.nih.gov/pubmed/31194881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13339
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