The development of colitis in Il10(−/−) mice is dependent on IL-22

Mice deficient in the IL-10 pathway are the most widely-used models of intestinal immunopathology.IL-17A is strongly implicated in gut disease in mice and humans, but conflicting evidence has drawn IL-17’s role in the gut into question.IL-22 regulates antimicrobial and repair activities of intestina...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Gunasekera, Dilini C., Ma, Jinxia, Vacharathit, Vimvara, Shah, Palak, Ramakrishnan, Amritha, Uprety, Priyanka, Shen, Zeli, Sheh, Alexander, Brayton, Cory F., Whary, Mark T., Fox, James G., Bream, Jay H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566780/
https://ncbi.nlm.nih.gov/pubmed/31932715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0252-3
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