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The development of colitis in Il10(−/−) mice is dependent on IL-22
Mice deficient in the IL-10 pathway are the most widely-used models of intestinal immunopathology.IL-17A is strongly implicated in gut disease in mice and humans, but conflicting evidence has drawn IL-17’s role in the gut into question.IL-22 regulates antimicrobial and repair activities of intestina...
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| 出版年: | Mucosal Immunol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566780/ https://ncbi.nlm.nih.gov/pubmed/31932715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0252-3 |
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