Spontaneous colitis in IL‐10‐deficient mice was ameliorated via inhibiting glutaminase1

Immunity imbalance and barrier damage in the intestinal mucosa are the main pathogenic factors of Crohn's disease (CD). Bis‐2‐(5‐phenylacetamido‐1,2,4‐thiadiazol‐2‐yl) ethyl sulfide (BPTES) is a glutaminase 1 (Gls1) inhibitor with the dual functions of increasing glutamine levels and immune reg...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Li, Jing, Zuo, Lugen, Tian, Yun, He, Yifan, Zhang, Zhichao, Guo, Pu, Ge, Yuanyuan, Hu, Jianguo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653008/
https://ncbi.nlm.nih.gov/pubmed/31211512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14471
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