Spontaneous colitis in IL‐10‐deficient mice was ameliorated via inhibiting glutaminase1

Immunity imbalance and barrier damage in the intestinal mucosa are the main pathogenic factors of Crohn's disease (CD). Bis‐2‐(5‐phenylacetamido‐1,2,4‐thiadiazol‐2‐yl) ethyl sulfide (BPTES) is a glutaminase 1 (Gls1) inhibitor with the dual functions of increasing glutamine levels and immune reg...

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Dettagli Bibliografici
Pubblicato in:J Cell Mol Med
Autori principali: Li, Jing, Zuo, Lugen, Tian, Yun, He, Yifan, Zhang, Zhichao, Guo, Pu, Ge, Yuanyuan, Hu, Jianguo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653008/
https://ncbi.nlm.nih.gov/pubmed/31211512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14471
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