Spontaneous colitis in IL‐10‐deficient mice was ameliorated via inhibiting glutaminase1

Immunity imbalance and barrier damage in the intestinal mucosa are the main pathogenic factors of Crohn's disease (CD). Bis‐2‐(5‐phenylacetamido‐1,2,4‐thiadiazol‐2‐yl) ethyl sulfide (BPTES) is a glutaminase 1 (Gls1) inhibitor with the dual functions of increasing glutamine levels and immune reg...

Full description

Saved in:
Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Li, Jing, Zuo, Lugen, Tian, Yun, He, Yifan, Zhang, Zhichao, Guo, Pu, Ge, Yuanyuan, Hu, Jianguo
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653008/
https://ncbi.nlm.nih.gov/pubmed/31211512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14471
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items