Spontaneous colitis in IL‐10‐deficient mice was ameliorated via inhibiting glutaminase1

Immunity imbalance and barrier damage in the intestinal mucosa are the main pathogenic factors of Crohn's disease (CD). Bis‐2‐(5‐phenylacetamido‐1,2,4‐thiadiazol‐2‐yl) ethyl sulfide (BPTES) is a glutaminase 1 (Gls1) inhibitor with the dual functions of increasing glutamine levels and immune reg...

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Publicado en:J Cell Mol Med
Autores principales: Li, Jing, Zuo, Lugen, Tian, Yun, He, Yifan, Zhang, Zhichao, Guo, Pu, Ge, Yuanyuan, Hu, Jianguo
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653008/
https://ncbi.nlm.nih.gov/pubmed/31211512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14471
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