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Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase
Adenosine triphosphate phosphoribosyltransferase (ATP-PRT) catalyzes the first step in histidine biosynthesis, a pathway essential to microorganisms and a validated target for antimicrobial drug design. The ATP-PRT enzyme catalyzes the reversible substitution reaction between phosphoribosyl pyrophos...
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| izdano v: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6693643/ https://ncbi.nlm.nih.gov/pubmed/28872824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00484 |
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