載入...

Synthesis and evaluation of tetrahydropyrazolopyridine inhibitors of anion exchange protein SLC26A4 (pendrin)

Pendrin is a transmembrane chloride/anion antiporter that is strongly upregulated in the airways in rhinoviral infection, asthma, cystic fibrosis and chronic rhinosinusitis. Based on its role in the regulation of airway surface liquid depth, pendrin inhibitors have potential indications for treatmen...

全面介紹

Na minha lista:
書目詳細資料
發表在:Bioorg Med Chem Lett
Main Authors: Zhu, Jie S., Lu, Julia Y., Tan, Joseph-Anthony, Rivera, Amber A., Phuan, Puay-Wah, Shatskikh, Marina E., Son, Jung-Ho, Haggie, Peter M., Verkman, Alan S., Kurth, Mark J.
格式: Artigo
語言:Inglês
出版: 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690761/
https://ncbi.nlm.nih.gov/pubmed/31281021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.07.003
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!