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Small-Molecule Inhibitors of Pendrin Potentiate the Diuretic Action of Furosemide
Pendrin is a Cl(−)/HCO(3)(−) exchanger expressed in type B and non-A, non-B intercalated cells in the distal nephron, where it facilitates Cl(−) absorption and is involved in Na(+) absorption and acid-base balance. Pendrin-knockout mice show no fluid-electrolyte abnormalities under baseline conditio...
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| Veröffentlicht in: | J Am Soc Nephrol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118489/ https://ncbi.nlm.nih.gov/pubmed/27153921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015121312 |
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