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Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice
The regulatory network of genes and molecules in sleep/wakefulness remains to be elucidated. Here we describe the methodology and workflow of the dominant screening of randomly mutagenized mice and discuss theoretical basis of forward genetics research for sleep in mice. Our high-throughput screenin...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689935/ https://ncbi.nlm.nih.gov/pubmed/31337678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906774116 |
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