Identification of mutations through dominant screening for obesity using C57BL/6 substrains

The discovery of leptin substantiated the usefulness of a forward genetic approach in elucidating the molecular network regulating energy metabolism. However, no successful dominant screening for obesity has been reported, which may be due to the influence of quantitative trait loci between the scre...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Hossain, Mohammad Sarowar, Asano, Fuyuki, Fujiyama, Tomoyuki, Miyoshi, Chika, Sato, Makito, Ikkyu, Aya, Kanno, Satomi, Hotta, Noriko, Kakizaki, Miyo, Honda, Takato, Kim, Staci J., Komiya, Haruna, Miura, Ikuo, Suzuki, Tomohiro, Kobayashi, Kimio, Kaneda, Hideki, Kumar, Vivek, Takahashi, Joseph S., Wakana, Shigeharu, Funato, Hiromasa, Yanagisawa, Masashi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009433/
https://ncbi.nlm.nih.gov/pubmed/27585985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32453
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