Identification of mutations through dominant screening for obesity using C57BL/6 substrains

The discovery of leptin substantiated the usefulness of a forward genetic approach in elucidating the molecular network regulating energy metabolism. However, no successful dominant screening for obesity has been reported, which may be due to the influence of quantitative trait loci between the scre...

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Publicado no:Sci Rep
Main Authors: Hossain, Mohammad Sarowar, Asano, Fuyuki, Fujiyama, Tomoyuki, Miyoshi, Chika, Sato, Makito, Ikkyu, Aya, Kanno, Satomi, Hotta, Noriko, Kakizaki, Miyo, Honda, Takato, Kim, Staci J., Komiya, Haruna, Miura, Ikuo, Suzuki, Tomohiro, Kobayashi, Kimio, Kaneda, Hideki, Kumar, Vivek, Takahashi, Joseph S., Wakana, Shigeharu, Funato, Hiromasa, Yanagisawa, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009433/
https://ncbi.nlm.nih.gov/pubmed/27585985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32453
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