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Identification of mutations through dominant screening for obesity using C57BL/6 substrains

The discovery of leptin substantiated the usefulness of a forward genetic approach in elucidating the molecular network regulating energy metabolism. However, no successful dominant screening for obesity has been reported, which may be due to the influence of quantitative trait loci between the scre...

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書誌詳細
出版年:Sci Rep
主要な著者: Hossain, Mohammad Sarowar, Asano, Fuyuki, Fujiyama, Tomoyuki, Miyoshi, Chika, Sato, Makito, Ikkyu, Aya, Kanno, Satomi, Hotta, Noriko, Kakizaki, Miyo, Honda, Takato, Kim, Staci J., Komiya, Haruna, Miura, Ikuo, Suzuki, Tomohiro, Kobayashi, Kimio, Kaneda, Hideki, Kumar, Vivek, Takahashi, Joseph S., Wakana, Shigeharu, Funato, Hiromasa, Yanagisawa, Masashi
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009433/
https://ncbi.nlm.nih.gov/pubmed/27585985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32453
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