Identification of mutations through dominant screening for obesity using C57BL/6 substrains

The discovery of leptin substantiated the usefulness of a forward genetic approach in elucidating the molecular network regulating energy metabolism. However, no successful dominant screening for obesity has been reported, which may be due to the influence of quantitative trait loci between the scre...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Hossain, Mohammad Sarowar, Asano, Fuyuki, Fujiyama, Tomoyuki, Miyoshi, Chika, Sato, Makito, Ikkyu, Aya, Kanno, Satomi, Hotta, Noriko, Kakizaki, Miyo, Honda, Takato, Kim, Staci J., Komiya, Haruna, Miura, Ikuo, Suzuki, Tomohiro, Kobayashi, Kimio, Kaneda, Hideki, Kumar, Vivek, Takahashi, Joseph S., Wakana, Shigeharu, Funato, Hiromasa, Yanagisawa, Masashi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009433/
https://ncbi.nlm.nih.gov/pubmed/27585985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32453
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