A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice

Sleep is an evolutionally conserved behavior from vertebrates to invertebrates. The molecular mechanisms that determine daily sleep amounts and the neuronal substrates for homeostatic sleep need remain unknown. Through a large-scale forward genetic screen of sleep behaviors in mice, we previously de...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Honda, Takato, Fujiyama, Tomoyuki, Miyoshi, Chika, Ikkyu, Aya, Hotta-Hirashima, Noriko, Kanno, Satomi, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Funato, Hiromasa, Yanagisawa, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187192/
https://ncbi.nlm.nih.gov/pubmed/30254177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810823115
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