A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice

Sleep is an evolutionally conserved behavior from vertebrates to invertebrates. The molecular mechanisms that determine daily sleep amounts and the neuronal substrates for homeostatic sleep need remain unknown. Through a large-scale forward genetic screen of sleep behaviors in mice, we previously de...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Honda, Takato, Fujiyama, Tomoyuki, Miyoshi, Chika, Ikkyu, Aya, Hotta-Hirashima, Noriko, Kanno, Satomi, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Funato, Hiromasa, Yanagisawa, Masashi
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187192/
https://ncbi.nlm.nih.gov/pubmed/30254177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810823115
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