Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice

The regulatory network of genes and molecules in sleep/wakefulness remains to be elucidated. Here we describe the methodology and workflow of the dominant screening of randomly mutagenized mice and discuss theoretical basis of forward genetics research for sleep in mice. Our high-throughput screenin...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Miyoshi, Chika, Kim, Staci J., Ezaki, Takahiro, Ikkyu, Aya, Hotta-Hirashima, Noriko, Kanno, Satomi, Kakizaki, Miyo, Yamada, Mana, Wakana, Shigeharu, Yanagisawa, Masashi, Funato, Hiromasa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2019
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689935/
https://ncbi.nlm.nih.gov/pubmed/31337678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906774116
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