Forward genetic analysis of sleep in randomly mutagenized mice

Sleep is a behavior conserved from invertebrates to vertebrates, and tightly regulated in a homeostatic manner. The molecular and cellular mechanism determining the amount of rapid eye movement sleep (REMS) and non-REMS (NREMS) remains unknown. Here we identified two dominant mutations affecting sle...

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Udgivet i:Nature
Main Authors: Funato, Hiromasa, Miyoshi, Chika, Fujiyama, Tomoyuki, Kanda, Takeshi, Sato, Makito, Wang, Zhiqiang, Ma, Jing, Nakane, Shin, Tomita, Jun, Ikkyu, Aya, Kakizaki, Miyo, Hotta, Noriko, Kanno, Satomi, Komiya, Haruna, Asano, Fuyuki, Honda, Takato, Kim, Staci J., Harano, Kanako, Muramoto, Hiroki, Yonezawa, Toshiya, Mizuno, Seiya, Miyazaki, Shinichi, Connor, Linzi, Kumar, Vivek, Miura, Ikuo, Suzuki, Tomohiro, Watanabe, Atsushi, Abe, Manabu, Sugiyama, Fumihiro, Takahashi, Satoru, Sakimura, Kenji, Hayashi, Yu, Liu, Qinghua, Kume, Kazuhiko, Wakana, Shigeharu, Takahashi, Joseph S, Yanagisawa, Masashi
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076225/
https://ncbi.nlm.nih.gov/pubmed/27806374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20142
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