Načítá se...
Effect of Sugar 2′,4′-Modifications on Gene Silencing Activity of siRNA Duplexes
In this study, we explore the effect of a library of 2′-, 4′-, and 2′,4′-modified uridine nucleosides and their impact on silencing firefly luciferase and on down-regulated in renal cell carcinoma (DRR) gene targets. The modifications studied were 2′-F-ribose, 2′-F-arabinose, 2′-OMe-ribose, 2′-F,4′-...
Uloženo v:
| Vydáno v: | Nucleic Acid Ther |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Mary Ann Liebert, Inc., publishers
2019
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686699/ https://ncbi.nlm.nih.gov/pubmed/31084536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2019.0792 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|