Design and enhanced gene silencing activity of spherical 2′-fluoroarabinose nucleic acids (FANA-SNAs)

Drug delivery vectors for nucleic acid therapeutics (NATs) face significant barriers for translation into the clinic. Spherical nucleic acids (SNAs) – nanoparticles with an exterior shell made up of DNA strands and a hydrophobic interior – have recently shown great potential as vehicles to improve t...

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Publicat a:Chem Sci
Autors principals: Fakih, Hassan H., Katolik, Adam, Malek-Adamian, Elise, Fakhoury, Johans J., Kaviani, Sepideh, Damha, Masad J., Sleiman, Hanadi F.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society of Chemistry 2021
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179377/
https://ncbi.nlm.nih.gov/pubmed/34164068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc06645a
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