Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells

Nucleic acid therapy can be beneficial for the local treatment of gastrointestinal diseases that currently lack appropriate treatments. Indeed, several oligonucleotides (ONs) are currently progressing through clinical trials as potential treatments for inflammatory bowel diseases. However, due to lo...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Moroz, Elena, Lee, Soo Hyeon, Yamada, Ken, Halloy, François, Martínez-Montero, Saúl, Jahns, Hartmut, Hall, Jonathan, Damha, Masad J, Castagner, Bastien, Leroux, Jean-Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056993/
https://ncbi.nlm.nih.gov/pubmed/27648924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.69
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