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Improving gene silencing of siRNAs via tricyclo-DNA modification

Small interfering RNAs (siRNAs) can be exploited for the selective silencing of disease-related genes via the RNA interference (RNAi) machinery and therefore raise hope for future therapeutic applications. Especially chemically modified siRNAs are of interest as they are expected to convert lead siR...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ittig, Damian, Luisier, Samuel, Weiler, Jan, Schümperli, Daniel, Leumann, Christian J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109438/
https://ncbi.nlm.nih.gov/pubmed/21687522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/adna.1.1.11385
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