Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55

Complement activation plays an important role in pharmacokinetic and performance of intravenously administered nanomedicines. Significant efforts have been directed toward engineering of nanosurfaces with low complement activation, but due to promiscuity of complement factors and redundancy of pathw...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Control Release
Prif Awduron: Gifford, Geoffrey, Vu, Vivian P., Banda, Nirmal K., Holers, V Michael, Wang, Guankui, Groman, Ernest, Backos, Donald, Scheinman, Robert, Moghimi, S. Moein, Simberg, Dmitri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684249/
https://ncbi.nlm.nih.gov/pubmed/30974134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.04.009
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