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Complement Inhibitors Block Complement C3 Opsonization and Improve Targeting Selectivity of Nanoparticles in Blood

Complement is one of the critical branches of innate immunity that determines the recognition of engineered nanoparticles by immune cells. Antibody-targeted iron oxide nanoparticles are a popular platform for magnetic separations, in vitro diagnostics, and molecular imaging. We used 60 nm cross-link...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Gaikwad, Hanmant, Li, Yue, Gifford, Geoffrey, Groman, Ernest, Banda, Nirmal K., Saba, Laura, Scheinman, Robert, Wang, Guankui, Simberg, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7528420/
https://ncbi.nlm.nih.gov/pubmed/32598839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.0c00342
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