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Immunoglobulin deposition on biomolecule corona determines complement opsonisation efficiency of preclinical and clinical nanoparticles

Deposition of complement factors (opsonisation) on nanoparticles may promote clearance from the blood by macrophages and trigger proinflammatory responses, but the mechanisms regulating the efficiency of complement activation are poorly understood. We previously demonstrated that opsonisation of sup...

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Podrobná bibliografie
Vydáno v:Nat Nanotechnol
Hlavní autoři: Vu, Vivian P., Gifford, Geoffrey B., Chen, Fangfang, Benasutti, Halli, Wang, Guankui, Groman, Ernest V., Scheinman, Robert, Saba, Laura, Moghimi, Seyed Moein, Simberg, Dmitri
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402998/
https://ncbi.nlm.nih.gov/pubmed/30643271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-018-0344-3
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