Anti-C1q autoantibodies amplify pathogenic complement activation in systemic lupus erythematosus

Por Holers, V. Michael
Publicado em 2004

Human C3 glomerulopathy provides unique insights into complement factor H–related protein function

Por Holers, V. Michael
Publicado em 2013

Autoimmunity to Citrullinated Proteins and the Initiation of Rheumatoid Arthritis

Por Holers, V. Michael
Publicado em 2013

Insights from Populations At-Risk for the Future Development of Classified Rheumatoid Arthritis

Por Holers, V. Michael
Publicado no Rheum Dis Clin North Am (2014)

Targeting mechanisms at sites of complement activation for imaging and therapy

Por Holers, V. Michael
Publicado no Immunobiology (2015)

Complement therapeutics

Por Lambris, John D., Holers, V. Michael., Ricklin, Daniel.
Publicado em 2013

Pre-Clinical Rheumatoid Arthritis: Identification, Evaluation and Future Directions for Investigation

Por Deane, Kevin D., Norris, Jill M., Holers, V. Michael
Publicado em 2010

Systemic Human CR2-Targeted Complement Alternative Pathway Inhibitor Ameliorates Mouse Laser-Induced Choroidal Neovascularization

Por Rohrer, Bärbel, Coughlin, Beth, Bandyopadhyay, Mausumi, Holers, V. Michael
Publicado em 2012

When and Where Does Inflammation Begin in Rheumatoid Arthritis?

Por Demoruelle, M. Kristen, Deane, Kevin D., Holers, V. Michael
Publicado em 2014

A Novel Targeted Inhibitor of the Alternative Pathway of Complement and Its Therapeutic Application in Ischemia/Reperfusion Injury

Por Huang, Yuxiang, Qiao, Fei, Atkinson, Carl, Holers, V. Michael, Tomlinson, Stephen
Publicado em 2008

A Citrullinated Fibrinogen-Specific T Cell Line Enhances Autoimmune Arthritis in a Mouse Model of Rheumatoid Arthritis

Por Cordova, Kristen N., Willis, Van C., Haskins, Kathryn, Holers, V. Michael
Publicado em 2013

A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an anti-C5aR1 antibody and C5 siRNA

Por Mehta, Gaurav, Scheinman, Robert I., Holers, V. Michael, Banda, Nirmal K.
Publicado no J Immunol (2015)

Mapping of the C3d Ligand Binding Site on Complement Receptor 2 (CR2/CD21) Using Nuclear Magnetic Resonance and Chemical Shift Analysis

Por Kovacs, James M., Hannan, Jonathan P., Eisenmesser, Elan Z., Holers, V. Michael
Publicado em 2009

Biophysical Investigations of Complement Receptor 2 (CD21 and CR2)-Ligand Interactions Reveal Amino Acid Contacts Unique to Each Receptor-Ligand Pair

Por Kovacs, James M., Hannan, Jonathan P., Eisenmesser, Elan Z., Holers, V. Michael
Publicado em 2010

Human Complement Receptor 2 (CR2/CD21) as a Receptor for DNA: Implications for its Roles in the Immune Response and the Pathogenesis of Systemic Lupus Erythematosus (SLE)

Por Asokan, Rengasamy, Banda, Nirmal K., Szakonyi, Gerda, Chen, Xiaojiang S., Holers, V. Michael
Publicado em 2012

Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction

Por Girardi, Guillermina, Yarilin, Dmitry, Thurman, Joshua M., Holers, V. Michael, Salmon, Jane E.
Publicado em 2006

Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions

Por Hannan, Jonathan P., Laskowski, Jennifer, Thurman, Joshua M., Hageman, Gregory S., Holers, V. Michael
Publicado no PLoS One (2016)

Complement receptor 2–mediated targeting of complement inhibitors to sites of complement activation

Por Song, Hongbin, He, Chun, Knaak, Christian, Guthridge, Joel M., Holers, V. Michael, Tomlinson, Stephen
Publicado em 2003

Role of initial protein phosphorylation events and localized release-activated calcium influx in B cell antigen receptor signaling

Por Lyubchenko, Taras, Nielsen, J. Paul, Miller, Sara M., Liubchenko, Ganna A., Holers, V. Michael
Publicado em 2009

Epstein-Barr Virus Promotes Interferon-α Production by Plasmacytoid Dendritic Cells

Por Quan, Timothy E., Roman, Robert M., Rudenga, Benjamin J., Holers, V. Michael, Craft, Joe
Publicado em 2010