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A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an anti-C5aR1 antibody and C5 siRNA

Rheumatoid Arthritis (RA) is an inflammatory autoimmune joint disease in which the complement system plays an important role. Of the several components of complement, current evidence points to C5 as the most important inducer of inflammation. Several groups generated antibodies or siRNAs or small m...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Mehta, Gaurav, Scheinman, Robert I., Holers, V. Michael, Banda, Nirmal K.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433857/
https://ncbi.nlm.nih.gov/pubmed/25917104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403012
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