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Systemic Human CR2-Targeted Complement Alternative Pathway Inhibitor Ameliorates Mouse Laser-Induced Choroidal Neovascularization

PURPOSE: Genetic associations and the presence of complement components within pathological structures of age-related macular degeneration (AMD) have generated the hypothesis that AMD is caused by chronic local complement activation. Since the majority of activity in the common terminal pathway resu...

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Autors principals: Rohrer, Bärbel, Coughlin, Beth, Bandyopadhyay, Mausumi, Holers, V. Michael
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406320/
https://ncbi.nlm.nih.gov/pubmed/22309197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2011.0212
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