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Human C3 glomerulopathy provides unique insights into complement factor H–related protein function
The study in this issue of the JCI by Tortajada et al. demonstrates that a duplication within the gene complement factor H–related 1 (CFHR1; encoding FHR1) leads to the production of an aberrant larger form of the protein. Elegant in vitro studies of the mutant and normal variants demonstrate an une...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3668810/ https://ncbi.nlm.nih.gov/pubmed/23728171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69684 |
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