Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions

Complement factor H-related protein 1 (CFHR1) is a complement regulator which has been reported to regulate complement by blocking C5 convertase activity and interfering with C5b surface association. CFHR1 also competes with complement factor H (CFH) for binding to C3b, and may act as an antagonist...

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Bibliographic Details
Published in:PLoS One
Main Authors: Hannan, Jonathan P., Laskowski, Jennifer, Thurman, Joshua M., Hageman, Gregory S., Holers, V. Michael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096715/
https://ncbi.nlm.nih.gov/pubmed/27814381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166200
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